PDE6 gamma (PDE6G) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1E11]

CAT#: TA503739AM

PDE6G (PDE6 gamma) mouse monoclonal antibody, clone OTI1E11 (formerly 1E11), Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE6G (RC216236, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE6G. Positive lysates LY419220 (100ug) and LC419220 (20ug) can be purchased separately from OriGene.

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  HEK293T cells transfected with either RC216236 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PDE6G antibody (TA503739), and then analyzed by flow cytometry.

Specifications

Product Data

• Clone Name: OTI1E11
• Applications: FC, WB
• Recommended Dilution: WB 1:2000, FLOW 1:100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human PDE6G(NP_002593) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 9.5 kDa
• Gene Name: phosphodiesterase 6G
• Database Link:
  NP_002593
  Entrez Gene 5148 Human
  UniProt ID P18545
• Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
• Synonyms: PDEG; RP57

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Progesterone-mediated oocyte maturation, Purine metabolism