Placental lactogen (CSH1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4D6]
CAT#: TA506816AM
CSH1 mouse monoclonal antibody, clone OTI4D6 (formerly 4D6), Biotinylated
Other products for "CSH1"
Specifications
Product Data | |
Clone Name | OTI4D6 |
Applications | IF, WB |
Recommended Dilution | WB 1:4000, IF 1:100 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CSH1(NP_072166) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 28.6 kDa |
Gene Name | chorionic somatomammotropin hormone 1 |
Database Link | |
Background | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008] |
Synonyms | CSA; CSH2; CSMT; FLJ75407; PL |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction |
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