Kallikrein 11 (KLK11) Rabbit Polyclonal Antibody

CAT#: TA590401

Rabbit Polyclonal Kallikrein-11 Antibody

Product Images

ELISA: Kallikrein-11 Antibody

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  Immunohistochemical staining of human salivary gland shows strong cytoplasmic and membranous positivity in ducts.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

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  Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

Specifications

Product Data

• Applications: ELISA, IF, IHC
• Recommended Dilution: ELISA: 1:100-1:2000; IHC: 1:650; IF: 1:162
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the Middle Region of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 0.96715 mg/ml
• Purification: The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
• Gene Name: kallikrein related peptidase 11
• Database Link:
  NP_659196
  Entrez Gene 11012 Human
• Background: Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
• Synonyms: PRSS20; TLSP
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein