Ku80 (XRCC5) Rabbit Polyclonal Antibody

CAT#: TA590469

Rabbit Polyclonal Ku80 Antibody


USD 409.00

In Stock*

Size
    • 100 ug

Other products for "XRCC5"

Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
Reactivities Human, Monkey, Mouse, Dog
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Formulation 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 1.01mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name X-ray repair cross complementing 5
Background Originally identified as an autoantigen, the Ku protein are nuclear proteins found in eukaryotes. They exist as a heterodimer consisiting of Ku 70 and Ku 80, migrating at approximately 70 and 80 kDa respectively. They bind to DNA ends at double strand breaks. The Ku proteins interact with the DNA-dependent protein kinase (DNA-PK) and participate in the targeting of DNA-PK to DNA. The Ku proteins may participate in numerous cellular processes, including DNA repair and replication, cell signalling, cell proliferation, transcriptional activation and apoptosis.
Synonyms KARP-1; KARP1; KU80; Ku86; KUB2; NFIV
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Non-homologous end-joining

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