ARFGEF2 Rabbit Polyclonal Antibody

CAT#: TA590572

Rabbit Polyclonal ARFGEF2 Antibody

Product Images

ELISA: ARFGEF2 Antibody

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  Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

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  Immunofluorescent staining of human cell line U-251 MG shows no positivity.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

Specifications

Product Data

• Applications: ELISA, IF, IHC
• Recommended Dilution: ELISA: 1:100-1:2000; IHC: 1:350; IF: 1:87
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the N Terminus Region of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 1.14599 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ADP ribosylation factor guanine nucleotide exchange factor 2
• Database Link:
  NP_006411
  Entrez Gene 10564 Human
  UniProt ID Q9Y6D5
• Background: BIG2 promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. ARFGEF2 plays an important role in vesicular and membrane trafficking from the trans-golgi network. It is also involved in the activation of ARFs (1,5, and 6) by accelerating replacement of bound GDP with GTP. It also acts as the activator of ADP-ribosylation factor GTPases that are essential for regulating vesicular traffic among intracellular organelles.
• Synonyms: BIG2; dJ1164I10.1; PVNH2
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT