IL17 (IL17A) Capture Mouse Monoclonal Antibody

CAT#: TA600555

IL-17A Capture mouse monoclonal antibody, clone OTI3D5

Product Images

IL17A ELISA with 3D5 Capture (TA600555) and 1E4 Detection (TA700556)) Antibodies. Substrate used: Recombinant Human IL17A (KEK293 cells expressed protein)

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  IL17A Luminex ELISA with 3D5 Capture (TA600555) and 1E4 Detection (TA700556)) Antibodies. Substrate used: Recombinant Human IL17A (KEK293 cells expressed protein)

Specifications

Product Data

• Applications: ELISA, LMNX
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human IL-17A (NP_002181) produced in 293 cell.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
• Predicted Protein Size: 17.5 kDa
• Gene Name: interleukin 17A
• Database Link:
  NP_002181
  Entrez Gene 3605 Human
  UniProt ID Q16552
• Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
• Synonyms: CTLA-8; CTLA8; IL-17; IL-17A; IL17

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction