IL17 (IL17A) Biotinylated detection Mouse Monoclonal Antibody
CAT#: TA700556
IL-17A HRP-Conjugated detection mouse monoclonal antibody, clone OTI1E4
USD 159.00
USD 396.00
Specifications
Product Data | |
Applications | ELISA, LMNX |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human IL-17A (NP_002181) produced in 293 cell. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
Predicted Protein Size | 17.5 kDa |
Gene Name | interleukin 17A |
Database Link | |
Background | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008] |
Synonyms | CTLA-8; CTLA8; IL-17; IL-17A; IL17 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
Product Manuals |
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