Kallikrein 8 (KLK8) Mouse Monoclonal Antibody [Clone ID: OTI3A12]

CAT#: TA801380

KLK8 mouse monoclonal antibody, clone OTI3A12 (formerly 3A12)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KLK8 (RC208152, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KLK8. Positive lysates LY416130 (100ug) and LC416130 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI3A12
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 33-260 of human KLK8 (NP_009127) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27.9 kDa
• Gene Name: kallikrein related peptidase 8
• Database Link:
  NP_009127
  Entrez Gene 11202 Human
  UniProt ID O60259
• Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
• Synonyms: HNP; NP; NRPN; PRSS19; TADG14

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane