Fos B (FOSB) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2F3]

CAT#: TA804227BM

Purified FOSB mouse monoclonal antibody, clone OTI2F3 (formerly 2F3), HRP conjugated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOSB (RC207004, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOSB. Positive lysates LY402011 (100ug) and LC402011 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI2F3
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-255 of human FOSB (NP_006723) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35.7 kDa
• Gene Name: FosB proto-oncogene, AP-1 transcription factor subunit
• Database Link:
  NP_006723
  Entrez Gene 14282 MouseEntrez Gene 2354 Human
  UniProt ID P53539
• Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: AP-1; G0S3; GOS3; GOSB

Reference Data

• Protein Families: Druggable Genome, Transcription Factors