ASPA Mouse Monoclonal Antibody [Clone ID: OTI1A11]

CAT#: TA805325S

ASPA mouse monoclonal antibody, clone OTI1A11 (formerly 1A11)

Product Images

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-ASPA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA805325)

• 

  Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-ASPA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA805325)

Specifications

Product Data

• Clone Name: OTI1A11
• Applications: IHC
• Recommended Dilution: IHC 1:150
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 77-313 of human ASPA (NP_000040) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35.6 kDa
• Gene Name: aspartoacylase
• Database Link:
  NP_000040
  Entrez Gene 11484 MouseEntrez Gene 79251 RatEntrez Gene 443 Human
  UniProt ID P45381
• Background: This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: ACY2; ASP

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alanine, aspartate and glutamate metabolism, Histidine metabolism