ROR beta (RORB) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3D7]

CAT#: TA806860AM

RORB mouse monoclonal antibody, clone OTI3D7 (formerly 3D7), Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RORB (RC208666, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RORB (1:2000). Positive lysates LY402058 (100ug) and LC402058 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI3D7
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG3
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-260 of human RORB(NP_008845) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51.9 kDa
• Gene Name: RAR related orphan receptor B
• Database Link:
  NP_008845
  Entrez Gene 225998 MouseEntrez Gene 309288 RatEntrez Gene 6096 Human
• Background: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
• Synonyms: bA133M9.1; NR1F2; ROR-BETA; RZR-BETA; RZRB

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors