PON3 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1A5]
Other products for "PON3"
Specifications
Product Data | |
Clone Name | OTI1A5 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 30-319 of human PON3(NP_000931) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 39.4 kDa |
Gene Name | paraoxonase 3 |
Database Link | |
Background | This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008] |
Synonyms | lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase |
Reference Data | |
Protein Families | Secreted Protein, Transmembrane |
Protein Pathways | Metabolic pathways |
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