PDGF Receptor alpha (PDGFRA) Mouse Monoclonal Antibody [Clone ID: OTI1H10]
CAT#: TA807641
PDGFRA mouse monoclonal antibody, clone OTI1H10 (formerly 1H10)
Size: 30 ul
Formulation: Carrier Free
Specifications
Product Data | |
Clone Name | OTI1H10 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 789-1089 of human PDGFRA(NP_006197) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 120.3 kDa |
Gene Name | platelet derived growth factor receptor alpha |
Database Link | |
Background | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012] |
Synonyms | CD140A; PDGFR-2; PDGFR2; RHEPDGFRA |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane |
Protein Pathways | Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
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