HDAC8 Mouse Monoclonal Antibody [Clone ID: OTI1B2]
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Other products for "HDAC8"
Specifications
Product Data | |
Clone Name | OTI1B2 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-243 of human HDAC8 (NP_060956) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 41.6 kDa |
Gene Name | histone deacetylase 8 |
Database Link | |
Background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
Synonyms | CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Documents
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FAQs |
Resources
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