Cryptochrome I (CRY1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6C6]

CAT#: TA809967BM

CRY1 mouse monoclonal antibody,clone OTI6C6, HRP conjugated


USD 420.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI6C6
Applications WB
Recommended Dilution WB 1:2000
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 502-584 of human CRY1(NP_004066) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 66.2 kDa
Gene Name cryptochrome circadian clock 1
Background This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
Synonyms PHLL1
Reference Data
Protein Families Druggable Genome
Protein Pathways Circadian rhythm - mammal

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.