HIST1H3F Mouse Monoclonal Antibody [Clone ID: 1D4F2]
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Specifications
Product Data | |
Clone Name | 1D4F2 |
Applications | IF, WB |
Reactivities | Broad |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | A peptide comprising amino acids 21-39 of human histone H3.1. This region is 100% identical in human histone H3.2 |
Specificity | HISTONE H3.1 |
Formulation | Phosphate buffered saline containing 0.035% Sodium Azide (NaN3)30% Glycerol Label: Purified State: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant Purified IgG - liquid |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | +4°C, -20°C if preferred |
Stability | Shelf life: one year from despatch. |
Gene Name | histone cluster 1, H3f |
Database Link | |
Background | Mouse anti Human histone H3.1 antibody, clone 1D4F2 recognizes histone H3 variant H3.1.Histone H3 is one of the four core histones that make up the nucleosome core particle. Nucleosomes are the smallest subunit of chromatin and are made up of 146 bp of DNA wrapped around an octamer comprised of pairs of the four core histones (H2A, H2B, H3, and H4) (Smith, 1991). In contrast to histone H3.3, incorporation of histone H3.1 and H3.2 into nucleosomes is replication dependent rather than occurring throughout the cell cycle (Tagami et al. 2004). |
Synonyms | H3/a; H3/b; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL |
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