Kallikrein 8 (KLK8) Mouse Monoclonal Antibody [Clone ID: UMAB84]

CAT#: UM500068

KLK8 mouse monoclonal antibody,clone UMAB84

Product Images

Western blot analysis of extracts (10ug) from 10 Human tissue by using anti-KLK8 monoclonal antibody at 1:500 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon;10: spleen).

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  Western blot of cell lysates (35ug) from 9 different cell lines (1: HepG2, 2: HeLa, 3: SV-T2, 4: A549, 5: COS7, 6: Jurkat, 7: MDCK, 8: PC-12, 9: MCF7). Diluation: 1:500

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  Western blot of mouse tissue lysates (20ug) from Uterus. Primary antibody diluation: 1:500. Secondary antibody dilution: Mouse TrueBlot® Ultra (1:1000).

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  Immunohistochemical staining of paraffin-embedded Human embryonic brain cortex tissue using anti-KLK8 mouse monoclonal antibody. (UM500068; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min)

Specifications

Product Data

• Clone Name: UMAB84
• Applications: IHC, WB
• Recommended Dilution: IHC 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human KLK8(NP_009127) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5~1.0 mg/ml (Lot Dependent)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27.9 kDa
• Gene Name: Homo sapiens kallikrein related peptidase 8 (KLK8), transcript variant 1, mRNA.
• Database Link:
  NP_009127
  Entrez Gene 11202 Human
  UniProt ID O60259
• Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq, Jul
• Synonyms: HNP; NP; NRPN; PRSS19; TADG14

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane