Chromogranin A (CHGA) Mouse Monoclonal Antibody [Clone ID: UMAB109]

CAT#: UM500076

CHGA mouse monoclonal antibody,clone UMAB109

Product Images

Western blot of human tissue lysates (15ug) from 10 different tissues (1: Testis, 2: Omentum, 3: Uterus, 4: Breast, 5: Brain, 6: Liver, 7: Ovary, 8: Thyroid, 9: Colon, 10: Spleen ). Diluation: 1:250.

• 

  Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-CHGA mouse monoclonal antibody. (UM500076; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min)

• 

  Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CHGA mouse monoclonal antibody. (UM500076; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min)

• 

  Immunohistochemical staining of paraffin-embedded human carcinoid tumor using anti-CHGA clone UMAB109 mouse monoclonal antibody at 1:200 with Polink2 Broad HRP DAB detection kit (UM500076; heat-induced epitope retrieval with 1mM EDTA buffer, pH8.0 at 95-100C

Specifications

Product Data

• Clone Name: UMAB109
• Applications: IHC, WB
• Recommended Dilution: IHC 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human CHGA(NP_001266) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5~1.0 mg/ml (Lot Dependent)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48.9 kDa
• Gene Name: Homo sapiens chromogranin A (CHGA), transcript variant 1, mRNA.
• Database Link:
  NP_001266
  Entrez Gene 1113 Human
  UniProt ID P10645
• Background: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008]
• Synonyms: CGA

Reference Data

• Protein Families: Druggable Genome, Secreted Protein