Human Fibronectin ELISA Kit
USD 320.00
3 Weeks*
Size
Other products for "FN1"
Specifications
Product Data | |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human Fibronectin |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 156pg/ml-10,000g/ml |
Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA, citrate). |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of human Fibronectin |
Sensitivity | <10pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Fibronectin(FN) also known as LETS, is identified on the surfFN of fibroblasts by labeling with radioactive compounds or specific antibodies. Fibronectin is a 430,000-dalton dimeric glycoprotein that exists in 2 forms, termed cellular and plasma fibronectin. Cellular and plasma fibronectins are heterodimers consisting of similar but not identical polypeptides. These two forms of FN differ in biologic activity. Fibronectins bind cell surfFNs and various compounds including collagen, fibrin, heparin, DNA, and actin. Because fibronectin stimulates endocytosis in several systems and promotes the clearance of particulate material from the circulation, it could function in the clearance of C1q-coated material such as immune complexes or cellular debris. Fibronectins are involved in cell adhesion, cell motility, opsonization, would healing, and maintenance of cell shape. LETS, encoded on chromosome 8, is responsible for the LETS protein expression in humans. Because LETS has been implicated in tumorigenicity and cellular transformation, it is of interest that rearrangement or modifications in the number of chromosome 8 have been associated with certain forms of cancer. The standard used in this kit is isolated from human plasma with the molecular mass of 200-250KDa. |
Gene Symbol | FN1 |
Standard Curve |
![]() Representative standard curve for Human Fibronectin PicoKine ELISA Kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.