Rat MIP-3 alpha/CCL20 ELISA Kit
USD 490.00
3 Weeks*
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Specifications
Product Data | |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Rat MIP-3 alpha/CCL20 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 7.8pg/ml-500pg/ml |
Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA). |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of rat MIP-3 alpha |
Sensitivity | <1pg/ml |
Reactivities | Rat |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Macrophage Inflammatory Protein 3alpha(MIP3alpha), also called Chemokine, cc motif, ligand 20(CCL20). The MIP-3alpha/CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3alpha/CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin. And Alanine MIP-3alpha and Serine MIP-3alpha, the two forms of MIP3alpha, that differ by one amino acid at the predicted signal peptide cleavage site. Both of them were chemically synthesized and tested for biological activity. And both flu antigen plus IL-2-activated CD4(+) and CD8(+) T lymphoblasts and cord blood-derived dendritic cells responded to Ser and Ala MIP-3alpha. |
Gene Symbol | Ccl20 |
Standard Curve |
![]() Representative standard curve for Rat MIP-3 alpha/CCL20 PicoKine ELISA Kit
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.