Human Methamphetamine ELISA kit

CAT#: EA100907

Human Methamphetamine ELISA kit

Specifications

Product Data

• Format: 8x12 divisible strips
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: 3 hours
• Signal: Colorimetric
• Sample Type: Serum
• Specificity: This kit is used for quantitative detection human Methamphetamine
• Reactivities: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Interference: No significant interference observed with available related molecules.
• Components:
  • 1. Microwells coated with polyclonal anti-d-methamphetamine: 12x8x1
  • 2. d-Meth-Conjugate: 12 ml
  • 3. Immunalysis Positive Ref. Std: 2 ml
  • 4. Neg Std: 1 ml
  • 5. TMB Substrate: 12 ml
  • 6. Stop Solution: 11 ml
• Background: The Methamphetamine Direct ELISA Kit is a specific and sensitive in-vitro test to detect the presence of d- methamphetamine in samples such as whole blood, oral fluids, serum, plasma and urine. While the assay will detect amphetamine use, interference by l-methamphetamine and pseudo-ephedrine is virtually nonexistent. Methamphetamine is a potent central nervous system stimulant with less peripheral actions than amphetamine. The (+)-isomer also referred to as d-methamphetamine is ten times more potent than the (-)-isomer, l-methamphetamine. Amphetamines act by inducing euphoria, irritability, anxiety and paranoia Methamphetamine is metabolized to its active metabolite amphetamine (via N- demethylation) and is further metabolized by hydroxylation and deamination of amphetamine. Urinary excretion rates are influenced by the urinary pH with acidic urine favoring the excretion of unchanged drug. Alkaline urine reduces the excretion of unchanged methamphetamine to less than 5% of the dose.