Human Troponin I ELISA kit

CAT#: EA101005

Human Troponin I ELISA kit

Product Images

Representative standard curve for Troponin I ELISA

Specifications

Product Data

• Format: 96-well strip plate
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: 4 hours
• Signal: Colorimetric
• Curve Range: Standard Curve Range: 0-75 ng/ml
• Sample Type: Human serum
• Sample Volume: 100 ul
• Specificity: This kit is used for quantitative detection of human Troponin I
• Sensitivity: Minimum Sensitivity: 1.0 ng/ml
• Reactivities: Human
• Cross Reactivity: N/A
• Interference: No significant interference observed with available related molecules.
• Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). TNNI3 (Troponin I Type 3 (Cardiac)) is a Protein Coding gene. Diseases associated with TNNI3 include cardiomyopathy, familial hypertrophic, 7 and cardiomyopathy, familial restrictive, 1. Among its related pathways are PI3K-Akt signaling pathway and ERK Signaling. GO annotations related to this gene include actin binding and protein domain specific binding. An important paralog of this gene is TNNI1.
• Gene Symbol: TNNI3
• Standard Curve:
  
  Representative standard curve for Troponin I ELISA