Human IL-10 HS ELISA Kit, 2 x 96-well (pre-coated)

CAT#: EA101246

Human IL-10 HS ELISA Kit, 2 x 96-well (pre-coated)

Product Images

Representative Standard Curve

Specifications

Product Data

• Format: 2 x 96-well (pre-coated)
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: 3h00min
• Signal: Colorimetric
• Curve Range: 1.56-50 pg/ml
• Sample Type: Serum, Plasma, Cell culture supernatant
• Sample Volume: 100 µl
• Specificity: Recognizes both natural and recombinant human IL-10
• Sensitivity: 1.30 pg/ml
• Cross Reactivity: No cross reactivity with other human cytokines
• Interference: No significant interference observed with available related molecules.
• Components: High Sensitivity ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
• Background: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2011]
• Gene Symbol: IL10
• Standard Curve:
  
  Representative Standard Curve