Human IL-1 beta ELISA Set, 5 x 96-well

CAT#: EA101333

Human IL-1 beta ELISA Set, 5 x 96-well

Specifications

Product Data

• Format: 5 x 96-well
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: From sample to end 3h45min
• Signal: Colorimetric
• Curve Range: 15.6-500 pg/ml
• Sample Type: Serum, Plasma, Cell culture supernatant
• Sample Volume: 100 µl
• Specificity: Recognizes both natural (pro and mature) and recombinant human IL-1b
• Sensitivity: 7 pg/ml
• Cross Reactivity: No cross reactivity with other human cytokines
• Components: ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
• Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
• Gene Symbol: IL1B