Human IL-13 ELISA Set, 5 x 96-well

CAT#: EA101343

Human IL-13 ELISA Set, 5 x 96-well

Specifications

Product Data

• Format: 5 x 96-well
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: From sample to end 1h45min
• Signal: Colorimetric
• Curve Range: 3.12-100 pg/ml
• Sample Type: Serum, Plasma, Cell culture supernatant
• Sample Volume: 100 µl
• Specificity: Recognizes both natural and recombinant human IL-13
• Sensitivity: 1.5 pg/ml
• Cross Reactivity: No cross reactivity with other human cytokines
• Components: ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
• Background: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
• Gene Symbol: IL13