Human IL-7 ELISA Set, 5 x 96-well

CAT#: EA101363

Human IL-7 ELISA Set, 5 x 96-well

Specifications

Product Data

• Format: 5 x 96-well
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: From sample to end 3h45min
• Signal: Colorimetric
• Curve Range: 6.25-200 pg/ml
• Sample Type: Serum, Plasma, Cell culture supernatant
• Sample Volume: 100 µl
• Specificity: Recognizes both natural and recombinant human IL-7
• Sensitivity: 3 pg/ml
• Cross Reactivity: No cross reaction with other human cytokines
• Components: ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
• Background: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. [provided by RefSeq, Dec 2010]
• Gene Symbol: IL7