Human IL-4 ELISpot Set, 20 x 96-well (plates not included)

CAT#: EA101443

Human IL-4 ELISpot Set, 20 x 96-well (plates not included)

Specifications

Product Data

• Format: 20 x 96-well (plates not included)
• Assay Type: Enzyme-Linked ImmunoSpot (ELISpot)
• Assay Length: 3h after cell stimulation
• Signal: Colorimetric
• Specificity: Recognizes natural human IL-4
• Cross Reactivity: No cross reactivity with other human cytokines
• Components: ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, and blocking reagent.
• Background: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
• Gene Symbol: IL4