Human IL-13 ELISpot Pair, 10 x 96-well

CAT#: EA101820

Human IL-13 ELISpot Pair, 10 x 96-well

Specifications

Product Data

• Format: 10 x 96-well
• Assay Type: Enzyme-Linked ImmunoSpot (ELISpot)
• Signal: Colorimetric
• Specificity: Recognizes both natural and recombinant human IL-13
• Cross Reactivity: No cross reactivity with other human cytokines
• Components: ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.
• Background: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
• Gene Symbol: IL13