Human IL-15 ELISA Kit, 1 x 48-well (pre-coated)

CAT#: EA101845

Human IL-15 ELISA Kit, 1 x 48-well (pre-coated)

Product Images

Representative Standard Curve

Specifications

Product Data

• Format: 1 x 48-well (pre-coated)
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: 3h45min
• Signal: Colorimetric
• Curve Range: 31.25-1000 pg/ml
• Sample Type: Serum, Plasma, Cell culture supernatant
• Sample Volume: 50 µl
• Specificity: Recognizes both natural and recombinant human IL-15
• Sensitivity: 18.3 pg/ml
• Cross Reactivity: No cross reaction with IL-2, IL-4, IL-7, IL-9, IL-10, IL-13, IL-21 and IFN-g
• Components: ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure.
• Background: The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
• Gene Symbol: IL15
• Standard Curve:
  
  Representative Standard Curve