Mouse Artn ELISA KIT (1 x 96 wells)
CAT#: EA102378
For Quantitative Detection of mouse Artemin in cell culture supernates, serum and plasma (heparin, EDTA).
USD 470.00
3 Weeks*
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse Artemin |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 31.2pg/ml-2000pg/ml |
Specificity | This kit is used for quantitative detection of Mouse Artemin |
Sensitivity | <10pg/ml |
Reactivities | Mouse |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | Artemin, also known as enovin or neublastin, is a protein that in humans is encoded by the ARTN gene. This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. |
Gene Symbol | Artn |
Standard Curve |
Mouse Artemin ELISA Kit standard curve
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.