Human Heparin Cofactor II (SERPIND1) ELISA KIT (1 x 96 wells)
CAT#: EA102650
For quantitative detection of human Serpin D1 in cell culture supernates, serum and plasma (EDTA, citrate) and urine.
USD 470.00
3 Weeks*
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human Serpin D1 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 0.78ng/ml-50ng/ml |
Specificity | This kit is used for quantitative detection of Human Serpin D1 |
Sensitivity | <0.1ng/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
|
Background | Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate. It is mapped to 22q11.21. This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. |
Gene Symbol | SERPIND1 |
Standard Curve |
Human Serpin D1 ELISA Kitstandard curve
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.