Mouse Fgfr4 ELISA KIT (1 x 96 wells)
CAT#: EA102761
For quantitative detection of mouse FGFR4 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
USD 470.00
3 Weeks*
Size
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse FGFR4 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 312pg/ml-20000pg/ml |
Specificity | This kit is used for quantitative detection of Mouse FGFR4 |
Sensitivity | <50pg/ml |
Reactivities | Mouse |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the FGFR4 gene. It is mapped to 13 B1; 13 29.8 cM. FGFR4 has also been designated as CD334 (cluster of differentiation 334). The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. |
Gene Symbol | Fgfr4 |
Standard Curve |
![]() Mouse FGFR4 ELISA Kit Standard Curve
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Documents
SDS |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.