Rat Lgmn ELISA KIT (1 x 96 wells)
CAT#: EA102777
For quantitative detection of rat Legumain in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
USD 470.00
3 Weeks*
Size
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Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Rat Legumain |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 31.2pg/ml-2000pg/ml |
Specificity | This kit is used for quantitative detection of Rat Legumain |
Sensitivity | <10pg/ml |
Reactivities | Rat |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
|
Background | Legumain is a protein that in humans is encoded by the LGMN gene. It is mapped to 6q32. This gene encodes a cysteine protease, legumain, that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. |
Gene Symbol | Lgmn |
Standard Curve |
![]() Rat Legumain ELISA Kit Standard Curve
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Documents
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.