Human Myeloperoxidase (MPO) ELISA Kit 1 x 96
USD 650.00
2 Weeks*
Size
Other products for "MPO"
Specifications
Product Data | |
Format | 8x12 divisible strips |
Assay Type | Sandwich |
Assay Length | 3.5 hours incubations; 0.5 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 0.312ng/ml-20ng/ml |
Sample Type | Human serum, plasma and other biological fluids. |
Sample Volume | 100µl |
Specificity | This kit is used for quantitative detection of Human MPO |
Sensitivity | 110pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene. MPO protein is a 150-kDa cationic heterotetramer consisting of two 15-kDa light chains and two variable-weight glycosylated heavy chains bound to a prosthetic heme group, arranged as a homodimer of heterodimers. MPO is most abundantly expressed in neutrophil granulocytes, and produces hypohalous acids to carry out their antimicrobial activity, including hypochlorous acid. It is a lysosomal protein stored in azurophilic granules of the neutrophil and released into the extracellular space during degranulation. Myeloperoxidase deficiency is a hereditary deficiency of the enzyme, which predisposes to immune deficiency. Recent studies have reported an association between elevated myeloperoxidase levels and the severity of coronary artery disease, and elevated MPO levels increased the risk for cardiovascular mortality. It has also been suggested that myeloperoxidase plays a significant role in the development of the atherosclerotic lesion and rendering plaques unstable. MPO could serve as a sensitive predictor for myocardial infarction. |
Gene Symbol | MPO |
Gene ID | 4353 |
Standard Curve |
Data image of Human Myeloperoxidase (MPO) ELISA Kit.
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Documents
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SDS |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.