Acid Phosphatase 2 (ACP2) (NM_001131064) Human 3' UTR Clone

CAT#: SC201066

3`UTR clone of acid phosphatase 2 lysosomal (ACP2) transcript variant 2 for miRNA target validation


Reconstitution Protocol

USD 560.00

4 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Vector pMirTarget
Species Human
Transfection Reporter RFP
Assay Reporter Luciferase
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Symbol ACP2
Synonyms acid phosphatase 2, lysosomal; Acp-2; LAP; OTTMUSP00000015308
ACCN NM_001131064
Insert Size 165
Sequence Data
>SC201066 3'UTR clone of NM_001131064
The sequence shown below is from the reference sequence of NM_001131064. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon


CAATTGGCAGAGCTCAGAATTCAAGCGATCGC

TCACTGAGGACAGGGTAAGAGTGGCCAGCCCTTCCCTGGGGTGGTGAGGGGACAGCTCTGGCCGTAGGCC
TGCTGATGCCAGGCTCCTTTTCCCGCTGCCTGTTTCCCCGCTTCGCTCTACAGCTGCTGAAGTTCCCGTT
GGGCCCATGTCCCCGTTATGAGCAG

ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_001131064.1
Summary The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]
Locus ID 53

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