SF3B2 (NM_006842) Human 3' UTR Clone
CAT#: SC201821
3`UTR clone of splicing factor 3b subunit 2 145kDa (SF3B2) for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | SF3B2 |
Synonyms | Cus1; SAP145; SF3b1; SF3B145; SF3b150 |
ACCN | NM_006842 |
Insert Size | 179 |
Sequence Data |
>SC201821 3'UTR clone of NM_006842
The sequence shown below is from the reference sequence of NM_006842. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CAGCAAGAAATATAAGGAGTTCAAGTTTTAGGTCCCCTCACACTAGCCCTTTTTTTGGCCCTACGTCTGG ATGCCTGGGCTTCACACAAGAACCACCTCTCCCGCAGTTCCCAAGGACTTGTCATTTCATGTTCTTATTT TAGACCTGTTTTGTAAATAAAGCTGTTTCCCAAGGAAAG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_006842.2 |
Summary | This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008] |
Locus ID | 10992 |
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