STING (TMEM173) (NM_198282) Human 3' UTR Clone

CAT#: SC204283

3`UTR clone of transmembrane protein 173 (TMEM173) nuclear gene encoding mitochondrial protein for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: TMEM173
• Synonyms: ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING; STING-beta
• ACCN: NM_198282
• Insert Size: 316
• Sequence Data:
  Insert Sequence

  >SC204283 3'UTR clone of NM_198282
  The sequence shown below is from the reference sequence of NM_198282. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAGTGGAATGGAAAAGCCCCTCCCTCTCCGCACGGATTTCTCTTGAGACCCAGGGTCACCAGGCCAGAGC
  CTCCAGTGGTCTCCAAGCCTCTGGACTGGGGGCTCTCTTCAGTGGCTGAATGTCCAGCAGAGCTATTTCC
  TTCCACAGGGGGCCTTGCAGGGAAGGGTCCAGGACTTGACATCTTAAGATGCGTCTTGTCCCCTTGGGCC
  AGTCATTTCCCCTCTCTGAGCCTCGGTGTCTTCAACCTGTGAAATGGGATCATAATCACTGCCTTACCTC
  CCTCACGGTTGTTGTGAGGACTGAGTGTGTGGAAGT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_198282.1
• Summary: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
• Locus ID: 340061