STING (TMEM173) (NM_198282) Human 3' UTR Clone
CAT#: SC204283
3`UTR clone of transmembrane protein 173 (TMEM173) nuclear gene encoding mitochondrial protein for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | TMEM173 |
Synonyms | ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING; STING-beta |
ACCN | NM_198282 |
Insert Size | 316 |
Sequence Data |
>SC204283 3'UTR clone of NM_198282
The sequence shown below is from the reference sequence of NM_198282. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CAGTGGAATGGAAAAGCCCCTCCCTCTCCGCACGGATTTCTCTTGAGACCCAGGGTCACCAGGCCAGAGC CTCCAGTGGTCTCCAAGCCTCTGGACTGGGGGCTCTCTTCAGTGGCTGAATGTCCAGCAGAGCTATTTCC TTCCACAGGGGGCCTTGCAGGGAAGGGTCCAGGACTTGACATCTTAAGATGCGTCTTGTCCCCTTGGGCC AGTCATTTCCCCTCTCTGAGCCTCGGTGTCTTCAACCTGTGAAATGGGATCATAATCACTGCCTTACCTC CCTCACGGTTGTTGTGAGGACTGAGTGTGTGGAAGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_198282.1 |
Summary | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
Locus ID | 340061 |
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