HYAL2 (NM_033158) Human 3' UTR Clone

CAT#: SC204531

3`UTR clone of hyaluronoglucosaminidase 2 (HYAL2) transcript variant 2 for miRNA target validation


Reconstitution Protocol

USD 560.00

4 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Vector pMirTarget
Species Human
Transfection Reporter RFP
Assay Reporter Luciferase
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Symbol HYAL2
Synonyms LUCA2
ACCN NM_033158
Insert Size 352
Sequence Data
>SC204531 3'UTR clone of NM_033158
The sequence shown below is from the reference sequence of NM_033158. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon


CAATTGGCAGAGCTCAGAATTCAAGCGATCGC

CTTTACCTGGACCTTGTAGGGGTCTCCTGCCTAGCTGCCTAGCAAGCTGGCCTCTACCACAAGGGCTCTC
TTAGGCATGTAGGACCCTGCAGGGGGTGGACAAACTGGAGTCTGGAGTGGGCAGAGCCCCCAGGAAGCCC
AGGAGGGCATCCATACCAGCTCGCACCCCCCTGTTCTAAGGGGGAGGGGAAGTCCCTGGGAGGCCCCTTC
TCTCCCTGCCAGAGGGGAAGGAGGGTACAGCTGGGCTGGGGAGGACCTGACCCTACTCCCTTGCCCTAGA
TAGTTTATTATTATTATTATTTTGGGGTCTCTTTTGTAAATTAAACATAAAACAATTGCTTCTCTGCTTG
GA

ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_033158.4
Summary This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR. [provided by RefSeq, Mar 2010]
Locus ID 8692

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