Apc11 (ANAPC11) (NM_001002244) Human 3' UTR Clone
CAT#: SC205214
3`UTR clone of anaphase promoting complex subunit 11 (ANAPC11) transcript variant 1 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | ANAPC11 |
Synonyms | APC11; Apc11p; HSPC214 |
ACCN | NM_001002244 |
Insert Size | 386 |
Sequence Data |
>SC205214 3'UTR clone of NM_001002244
The sequence shown below is from the reference sequence of NM_001002244. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC ACCTGGCTCTCGCTGGAGGGGCATCCTGAGACTCCTTCCTCATGCTGGCGCCGATGGCTGCTGGGGACAG CGCCCCTGAGCTGCAACAAGGTGGAAACAAGGGCTGGAGCTGCGTTTGTTTTGCCATCACTATGTTGACA CTTTTATCCAATAAGTGAAAACTCATTAAACTACTCAAATCTTGCTGGAGGCCTCTGGGTGCCTGTGTTC TCGGCATATAGATGTGGTCTCGGTGTGTTTTGATATGAAAACTCTCATGAATAAACATCTCCGTGAAACG CCAAGGCCCTCGTCAAACCCTGAGTCATGACTGGGAGGAGAAGGAGCAGGATCAGACGGTAGAGCCTGGG GCATGCTCTTCAGGCATGCTCTTGCCTGCTGGATTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001002244.1 |
Summary | Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProtKB/Swiss-Prot Function] |
Locus ID | 51529 |
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