PMVK (NM_006556) Human 3' UTR Clone

CAT#: SC205444

3`UTR clone of phosphomevalonate kinase (PMVK) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: PMVK
• Synonyms: HUMPMKI; PMK; PMKA; PMKASE; POROK1
• ACCN: NM_006556
• Insert Size: 443
• Sequence Data:
  Insert Sequence

  >SC205444 3'UTR clone of NM_006556
  The sequence shown below is from the reference sequence of NM_006556. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGGAGCAGTTGGAGAACCTGATAGAATTTATCCGCTCCAGACTTTAGTCACTAGGTTCTAGGAGTGAGCT
  GGGGCCTGCTGAGGTGGGGGTGGGGCTGACTCTGCAAAATGGGGGTGTCCCCCGATCCTGGCCGAGGTGA
  GGAACAGACAGGGGGGGTCTAGATTCTGAGGGGGTTGGTGGATATTGGGCAAGGCAGGAAACCTCTGGAG
  ACCTCATTTTCTCCATGGGGAAGACAGCCATGCTCTTCAGGAGGAGACTCCAAGGGCAAAGGAGGGTGTC
  TTGGCTGTGCTTGAAGGCGAAACCCTGCCATATCCCCAGTGCCAGTCCCCTCAGCCTGTGGTGGCCTTGC
  ATCCTGACTGGATGTTCTCAGCCCCTTGTTCTGGGCAAGAACCCAGAGCTCCCCAGTGTGGATACTAATA
  AACCTCTTGGAGCACACTCTCAG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_006556.3
• Summary: This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
• Locus ID: 10654