HDAC8 (NM_018486) Human 3' UTR Clone

CAT#: SC207801

3`UTR clone of histone deacetylase 8 (HDAC8) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: HDAC8
• Synonyms: CDA07; CDLS5; HD8; HDACL1; KDAC8; MRXS6; RPD3; WTS
• ACCN: NM_018486
• Insert Size: 535
• Sequence Data:
  Insert Sequence

  >SC207801 3'UTR clone of NM_018486
  The sequence shown below is from the reference sequence of NM_018486. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GGGAATCTGAAGCATGTGGTCTAGTTGACAGAAAGAGATCAGGTTTCCAGAGCTGAGGAGTGGTGCCTAT
  AATGAAGACAGCGTGTTTATGCAAGCAGTTTGTGGAATTTGTGACTGCAGGGAAAATTTGAAAGAAATTA
  CTTCCTGAAAATTTCCAAGGGGCATCAAGTGGCAGCTGGCTTCCTGGGGTGAAGAGGCAGGCACCCCAGA
  GTCCTCAACTGGACCTAGGGGAAGAAGGAGATATCCCACATTTAAAGTTCTTATTTAAAAAAACACACAC
  ACACAAATGAAATTTTTAATCTTTGAAAATTATTTTTAAGCGAATTGGGGAGGGGAGTATTTTAATCATC
  TTAAATGAAACAGATCAGAAGCTGGATGAGAGCAGTCACCAGTTTGTAGGGCAGGAGGCAGCTGACAGGC
  AGGGTTTGGGCCTCAGGACCATCCAGGTGGAGCCCTGGGAGAGAGGGTACTGATCAGCAGACTGGGAGGT
  GGGGAGAAGTCCGCTGGTGTTGTTTTAGTGTTATATATCTTTGGT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_018486.2
• Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
• Locus ID: 55869