QPRT (NM_014298) Human 3' UTR Clone

CAT#: SC207976

3`UTR clone of quinolinate phosphoribosyltransferase (QPRT) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: QPRT
• Synonyms: HEL-S-90n; QPRTase
• ACCN: NM_014298
• Insert Size: 609
• Sequence Data:
  Insert Sequence

  >SC207976 3'UTR clone of NM_014298
  The sequence shown below is from the reference sequence of NM_014298. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CTGTTTGCCAAAGAGGTGGCTCCAGTGCCCAAAATCCACTAGTCCTAAACCGGAAGAGGATGACACCGGC
  CATGGGTTAACGTGGCTCCTCAGGACCCTCTGGGTCACACATCTTTAGGGTCAGTGGCCAATGGGGCACA
  TTTGGCACTAGCTTGAGCCCAACTCTGGCTCTGCCACCTGCTGCTCCTGTGACCTGTCAGGGCTGACTTC
  ACCTCTGCTCATCTCAGTTTCCTAATCTGTAAAATGGGTCTAATAAAGGATCAACCACATGGGGTTCTGC
  GGTGATAATGAGCACATAGTGAGGGGTCAGCAAATGTCAGAAGTTACCTGGGACAGCCGGGCACGATGGC
  TCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGAAGATCACTTGAGTTCAGGAGTTTGAGACC
  AGCCTGGCCAACATGGTGAAACCCCATCTCTACCAAAAATAGAAGAATTAGCTGGGTGTGGTGGCACGCG
  CCTGTAATCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAAGTGGAGGTTGCAGT
  GAGCTGATGGTGCCACTGCACTCCAGCCTGGGTGATAGAGCGAGACTCT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_014298.3
• Summary: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
• Locus ID: 23475