MCM3 (NM_002388) Human 3' UTR Clone
CAT#: SC208013
3`UTR clone of minichromosome maintenance complex component 3 (MCM3) for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | MCM3 |
Synonyms | HCC5; P1-MCM3; P1.h; RLFB |
ACCN | NM_002388 |
Insert Size | 591 bp |
Sequence Data |
>SC208013 3'UTR clone of NM_002388
The sequence shown below is from the reference sequence of NM_002388. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC ATGGTGTCTGAGGGCATCATCTTCCTCATCTGAGGAGGCCTCGTCTCTGAACTTGGGTTGTGCCGAGAGA GTTTGTTCTGTGTTTCCCACCCTCTCCCTGACCCAAGTCTTTGCCTCTACTCCCTTAACAGTGTTGAATT CAACTGAAGGCGAGGAATGTTGGTGATGAAGCTGAGTTCAGGACTCGGTGGACCCTTTGGGAATGGGTCA TGAAAGCTGCCATGGGGTGAGGAAAGAGGAGACAGTGGGAGAGGACAATGACTATTGCATCTTCATTGCA AAAGCACTGGCTCATCCGCCCTACTTCCCATCCCACACAAACCCAATTGTAAATAACATATGACTTCTGA GTACTTTTGGGGGCACAACTGTTTTCTGTTTGCTGTTTTTTTGTTTTGTTTTTTTTCTCCAGAGCACTTT GGTCTAGACTAGGCTTTGGGTGGTTCCAATTGGTGGAGAGAAGCTCTGAGGCACGTCATGCAGGTCAAGA AAGCTTTCTTTGCAGTAGCACCAGTTAAGGTGAATATGTATTGTATCACAAAACAAACCCAATATCCAGA TGAATATCCGAGATGTTGAATAAACTTAGCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_002388.3 |
Summary | 'The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018]' |
Locus ID | 4172 |
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