CYP46 (CYP46A1) (NM_006668) Human 3' UTR Clone

CAT#: SC208324

3`UTR clone of cytochrome P450 family 46 subfamily A polypeptide 1 (CYP46A1) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: CYP46A1
• Synonyms: CP46; CYP46
• ACCN: NM_006668
• Insert Size: 571
• Sequence Data:
  Insert Sequence

  >SC208324 3'UTR clone of NM_006668
  The sequence shown below is from the reference sequence of NM_006668. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  ACCACCCCCCTGCTGAGGGGGCCTCCAGGCAGGACGAGACTCCTCGGGCAAGGGCCGTGCCCGCCCACCT
  CTGCTGCCCACGGCCACCCACCCTTCTCCCCTGCCCCGTCCCCTGGGCCACCCTTCACGCTGGCTTCCAG
  CGGGCCCTCTGCCGACCGCCTGCTTCACACCCCTCAGCGCTCCCTGTCGCCTGCGGACTCCATGGCCCTT
  CCTGGACTGGCCCTTGCCCAACTCCCAGCCACCACCACTGTCCCTACCACTGAGCCCTTGCACAGGCCAC
  TTGCTCAGACGAGACACCCTAACTCTTGCTCACTCCCTAAAGCCCTCTTCAGGGGTCACCTCCTCCAAGA
  AGCCCTCCTTGCCACCCCCCGCCGGCAGGGGCCCCTCCTCTGTGCTCCCTCGGTCACCTGTGCTACCTCT
  AACACCACACTGACCACACTGTATCGTGAGTGTCCGTTGACGTGACCAATTGCCCTGCCAGGCTGTCAGC
  GCCTCAAGGGTAGGGTCTGCGTGTGATTTGTCTCTGAGCCCCCTGTGCCCACCCAGGGCCCGGCACAGAG
  TCGATGCTCAA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_006668.1
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
• Locus ID: 10858