FLASH (CASP8AP2) (NM_001137668) Human 3' UTR Clone
CAT#: SC208353
3`UTR clone of caspase 8 associated protein 2 (CASP8AP2) transcript variant 3 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | CASP8AP2 |
Synonyms | CED-4; FLASH; RIP25 |
ACCN | NM_001137668 |
Insert Size | 647 |
Sequence Data |
>SC208353 3'UTR clone of NM_001137668
The sequence shown below is from the reference sequence of NM_001137668. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GATTCCAGCAGCTAATGAAGCTCTTTGAAAAGTCAAAATGCAGATAAGTTGCTGAATTCCTGGGACTCTT AACTGATATTGCATACTACACAGAAGCTTCAAATTCCTCATGTTTTAAATGAGCACTAGAGGGAGGTTTA TCACCTTTTTGGTTACCAGATGATAATCTATATTTGTTATTACTCAGTGACTCTCTAATTTCACATCAGC ATGTTCAGCTTGTGCTAGTCATCATTCTGATTTGCTTATCTGTTTTTGGTCAAAATATTTATTTTTAAAC ATGTTAGAACTTACCAAAATGAAAGCAACAGTGATGTATTGAAATCTTAGTTTTGATATTTTAAAGAAAT GACTTTCTAGATTAAAAAAATAGTTTTGTAGCATTTTAAACTTAGTGACTATTTAGTTCAATTGTTCATC CATTTTTTATTTGCTTTTATAATTGCCTCCTTGTTTTGGTATATTGTAAAATAATTTAAATAATGTATTT ATAAATATGTATAATTATGATGTAAAATACCGTGTGTATATGTATGTATGTGTGTTTCTGTATATGCACA CACATAAACGGCTTTGCCTAGCCAAGGATTTTTTTTATCTGTATAAAACTTTTTGTATAAAGTTTGCTTT CAATAACAGTAATGTAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001137668.1 |
Summary | This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2008] |
Locus ID | 9994 |
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