CYP7B1 (NM_004820) Human 3' UTR Clone

CAT#: SC208711

3`UTR clone of cytochrome P450 family 7 subfamily B polypeptide 1 (CYP7B1) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: CYP7B1
• Synonyms: CBAS3; CP7B; SPG5A
• ACCN: NM_004820
• Insert Size: 701
• Sequence Data:
  Insert Sequence

  >SC208711 3'UTR clone of NM_004820
  The sequence shown below is from the reference sequence of NM_004820. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGTATCCAGATTCTGATGTTTTATTTAGATACAAAGTGAAATCTTAGAGAAGCTAAAAGGAAAGAAAATA
  AATCTATCAAAATTACCCTAAACATCCTAAGCTCATCTATTTCTTTTTAATTTCTGCAAATGTAATTGAT
  TTATTTGTTTAAAAAGCGCTAATTTCTATTTGATCTGATATCAGTCCAGTTTGTCCTTAGTCACAAAGCC
  CATCATAATATAAAACAGGATGGTGGCAGGAAAATGGACATCAAAATCAACTTAAGGGTAGGCTCAAAAC
  AGGGTTGTTGTTGTTTTTTTAGTTTCTCCTTGTTGTGATTTTCACCTGTTATAATAAATGTACCTTCACA
  CCAATAGATTGGGCACTGTGGAATTTAAATCACTCAAATTGTTCTCTAATATGTAAAATTACACTTTGAA
  CTACTAGAAAATTGTGCTGGAAATGGACACAGTCTAACAAATTCCAAATTCTCACAGAAGAAGGAAATTG
  AATTTCCATGAGTTACACTGGATGAAAATGTTCCCTTCAAGTATAATATTAATAATACCTATATTTCCAG
  GGTATGTGTGCATTAAATGAGTTTCACAGTAGATTGAATGCTTCAACTTCACTTCAATATTTAATCATGC
  ATAAATGTTCCTTATTACTTTGTATACTATGGCTCAATAGAACAAAATTTCTGGTTACATAAGACCTTTC
  A
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_004820.3
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
• Locus ID: 9420