IL12RB1 (NM_153701) Human 3' UTR Clone
CAT#: SC208722
3`UTR clone of interleukin 12 receptor beta 1 (IL12RB1) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | IL12RB1 |
Synonyms | CD212; IL-12R-BETA1; IL12RB; IMD30 |
ACCN | NM_153701 |
Insert Size | 670 bp |
Sequence Data |
>SC208722 3'UTR clone of NM_153701
The sequence shown below is from the reference sequence of NM_153701. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GGATTACAGGCATCTGCCACCATACCCGGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCACCACGTT GGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGTTGGGATTA TAGGCGTGAGCCACCATGCCCAGCCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGCCC AGGCTGGTCTCAAACTCCTGCCCTCAGGTGATCCACCCACCTCAGCCTCTCAAAGTGCTGGGATTACAGG TGTGAGCCACTGTGGCCGACCTACTATTTTTATTATTTTTGAGCTAGGTTCTCAGTCTGTTGGCAGACTG GAGTGCAATCATGGCTCACTGCAGCCTTGAACTCCCAGACTCAAGTGATCCTTCCACCTCAGCCTCTGGA GTAGCTGGGACTACAGACATGCACCACCACACCTGGTTAATTTTTTATTTTTATTTTTTGTAGAGACAGG TGTCTCTCTACGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGTGATCCACCCATCTCCACCTCCCA AAGTGCTAGGATTACAGGCGTGAGCCACCGTACCCAGCCTGGTCCCATATCATAGTGAAATGGTGCCTGT AAAGCTCTCAGCATTGGCTTGGCACATGCAGTTGGTACTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_153701.1 |
Summary | 'The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]' |
Locus ID | 3594 |
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