beta Arrestin 1 (ARRB1) (NM_020251) Human 3' UTR Clone
CAT#: SC209296
3`UTR clone of arrestin beta 1 (ARRB1) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | ARRB1 |
Synonyms | ARB1; ARR1 |
ACCN | NM_020251 |
Insert Size | 772 bp |
Sequence Data |
>SC209296 3'UTR clone of NM_020251
The sequence shown below is from the reference sequence of NM_020251. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC AGGAAGAGGAGGATGGTACCGGCTCTCCACAGCTCAACAACAGATAGACGGGCCGGCCCTGCCTCCACGT GGCTCCGGCTCCACTCTCGTGCACTCGGATGCTTACTCGTCTTCTTCCTGTTCTGGTTTCTTTTCCCCTT TGTTCTTCCAGTTTCTACCAGGGGGCCCCGTGGGCTTCCAGATCACGGTGATGAACCTCTGGCCTCAGGA TTGGCCCCACATCACCACGCCAACAGGACCACAGCGCACTGGCTCCACCCCATCTCTGCCATCTCCACTC CCCTCCTTTTCATGCTGTCTCCCAGAAAAGCTGCCAGGGCTCTGGCCTTGGAATTGGACTTGAGATGGGG AGCAGACAGGGGAGGATGGGGAATGTGGGACACGGTGTGGTGGGCATGAGGGCTTGGAGGGGTGGGGATG AGGGCTCAAGACACGAGAGAAGATGTCCACGGTCCCAGGTGGTTAACAAAGTTCTGGCAGCTAAAAGATG ACCGCGTTGAAGGCCACCTCCTTCTGGCTGGGAGGGGCAGAACTGTGGACAGATTCTCAATGCCTTTTTG AAGTTCTGACCCACCAAAGACCTTCTGCCTTCACCCTCCTCCCCACCTGATGTCCCTCTGTGTCTGATAG TGATGTTGGTGAAAGTTCGTAGACCCCAGGAGTAGAGAAAAGCAACTGGACTGACTTTCTTACCAGCAGT TACCTAGACTGAGGCAAGCTGTGTGGACTCACCCAAGTATATTTCAGTACTGTCAGGCTGTGACATCTTA GC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_020251.2 |
Summary | 'Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]' |
Locus ID | 408 |
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