FLT3 (NM_004119) Human 3' UTR Clone
CAT#: SC209844
3`UTR clone of fms-related tyrosine kinase 3 (FLT3) for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | FLT3 |
Synonyms | CD135; FLK-2; FLK2; STK1 |
ACCN | NM_004119 |
Insert Size | 772 bp |
Sequence Data |
>SC209844 3'UTR clone of NM_004119
The sequence shown below is from the reference sequence of NM_004119. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC AGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAAC AGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCAC CAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATC CTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAG GCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTG CTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAG TGATATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTA TAATTAGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACATT CCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAGCTATGGTTGTCACAGCCT AAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGTGTTCTACCATAAAGAGT AATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGAAGTAACATGGAGGATTAG TA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_004119.2 |
Summary | 'This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]' |
Locus ID | 2322 |
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