LYK5 (STRADA) (NM_001003786) Human 3' UTR Clone

CAT#: SC209975

3`UTR clone of STE20-related kinase adaptor alpha (STRADA) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: STRADA
• Synonyms: LYK5; NY-BR-96; PMSE; Stlk; STRAD; STRAD alpha
• ACCN: NM_001003786
• Insert Size: 786
• Sequence Data:
  Insert Sequence

  >SC209975 3'UTR clone of NM_001003786
  The sequence shown below is from the reference sequence of NM_001003786. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GTGGACGATTGGGAGTTCTGAGCCTCTGCAAACTGTGCGCATTCTCCAGCCAGGGATGCAGAGGCCACCC
  AGAGGCCCTTCCTGAGGGCCGGCCACATTCCCGCCCTCCTGGGCAGATTGGGTAGAAAGGACATTCTTCC
  AGGAAAGTTGACTGCTGACTGATTGGGAAAGAAAATCCTGGAGAGACACTTCACTGCTCCAAGGCTTTTG
  AGACACAAGGGAATCTCAACAACCAGGGATCAGGAGGGTCCAAAGCCGACATTCCCAGTCCTGTGAGCTC
  AGGTGACCTCCTCCGCAGAAGAGAGATGCTGCTCTGGCCCTGGGAGCTGAATTCCAAGCCCAGGGTTTGG
  CTCCTTAAACCCGAGGACCGCCACCTCTTCCCAGTGCTTGCGACCAGCCTCATTCTATTTAACTTTGCTC
  TCAGATGCCTCAGATGCTATAGGTCAGTGAAAGGGCAAGTAGTAAGCTGCCTGCCTCCCTTCCCTCAGAC
  CTCTCCCTCATAATTCCAGAGAAGGGCATTTCTGTCTTTTTAAGCACAGACTAAGGCTGGAACAGTCCAT
  CCTTATCCCTCTTCTGGCTTGGGCCCTGACACCTAAGTCTTTCCCACGGTTTATGTGTGTGCCTCATTCC
  TTTCCCACCAAGAATCCATCTTAGCGCCTCCTGCCAGCTGCCCTGGTGCTTTCTCCAAGGGCCATCAGTG
  TCTTGCCTAGCTTGAGGGCTTAAGTCCTTATGCTGTGTTAGTTTCGTTGTCAGAACAAATTAAAATTTTC
  AGAGACGCTGCTGGAG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_001003786.2
• Summary: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009]
• Locus ID: 92335